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Drug eruption:
An eruption or solitary lesion of skin is caused by a number of drugs taking internally .Nearly every drug can have untoward effects but it’s not necessary to affect every individual.
Susceptibility
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Patient with hepatic impairment
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Patient with renal insufficiency
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Patient with history of dermatitis, eczema, urticaria, erythema, induced by drugs.
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Patients with history of photosensitivity, allergy, preexisting skin disorder and with serum sickness syndrome.
Common drug eruptions.
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Urticaria
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Eczema
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Hair loss
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Pruritis
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Erythema nodosum and erythema multiforme.
Common drugs involved
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Codeine and opiates
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NSAIDs and aspirin
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Angiotensin convertase enzyme
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Allopurinol, sulphonamide, penicillin,
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Methyldopa, phenytoin, gold and oral contraceptives.
Treatment
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Antihistamines
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Corticosteroids
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Removal of drug causing sensitivity
